DIRECT ELECTRON: TRANSFORMING ELECTRON MICROSCOPY SINCE 2007

Direct Electron was founded in 2007 with the specific aim of developing and delivering ultra-high performance cameras for electron microscopy (EM).

Our vision—Innovation Propelling Discovery—focuses our effort on our customers. We combine relevant technological innovation with unique features and a commitment to an unprecedented level of customer service. Ultimately, our technology empowers customers to achieve better science, faster.

Our pioneering Direct Detection Device (DDD®) camera technology expands the frontiers of what is possible and gives our customers a competitive edge.

Direct Electron continues to aggressively push the boundaries of EM camera technology. Our research and development springs out of partnerships between public organizations, academia, and industry. For example, our pioneering Direct Detection Device was developed in collaboration with the University of California San Diego (UCSD) with generous support from the US National Institutes of Health (NIH).

INNOVATION

Our passion is innovation. Working in partnership with academia and public/private institutions, Direct Electron continues to deliver a stream of innovations for TEM.

PROPELLING

Direct Electron’s service and support set us apart. Working together, we can help maximize your productivity and propel you towards your next discovery.

discovery

Remove the limits imposed by your equipment. Our cameras are uniquely designed to deliver the highest quality results for a wide-range of TEM experiments.

2004Pioneered Direct Detection for TEM
2008Introduced drift correction using movie frames from a direct detector
2008First to demonstrate electron tomography with a direct detector
2009Introduced single electron counting with a direct detection camera
2010Introduced the DE-12 as the first commercial direct detector for TEM
2011First demonstration of cryo-EM 3D reconstruction using a direct detector
2012First to directly visualize and correct beam-induced specimen movement of cryo specimens
2012Achieved breakthrough with Cryo-EM 3D reconstructions surpassing 3/4 Nyquist resolution for the first time
2012Attained sub-nm resolution 3D reconstructions using images collected at less than 40 kx magnification
2013Developed "damage compensation" technique to enhance SNR across spatial frequencies
2013Achieved near-atomic resolution cryo-EM 3D reconstruction using a direct detector
2014Introduced the first commercial 8k × 8k direct detection camera (DE-64)
2014Pioneered large-format, high-speed in situ movie acquisition with a direct detector
2014Demonstrated energy filtered TEM (EFTEM) with a direct detection camera and movie-mode
2015Developed the first commercial MAPS direct detector for low-kV electron microscopy
2019Developed the DE-FreeScan programmable scan generator for 4D STEM
2020First to develop and offer a photoblind sensor for a direct detector for TEM
2020Created the first event-based MAPS detector for electron counting (Apollo)
2021Created the first ultra high frame rate MAPS detector for 4D STEM (Celeritas)
2022Patented high-dynamic range counting to enhance 4D STEM, diffraction, and EELS results with MAPS detectors
2022Patented technique for elemental mapping of labeled biological specimens using 4D STEM
2023Record 1.85 Å resolution for a Cryo-EM helical reconstruction
2023Record 0.5 Å resolution reported for a microcrystal electron diffraction dataset

Industry Firsts

WITH GUIDANCE FROM OUR TEAM OF PH.D MICROSCOPISTS

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