BHELLA GROUP: 2Å RESULTS

HIGH-RESOLUTION RECONSTRUCTION OF LUMAZINE SYNTHASE

The fascinating icosahedral structure shown here is Lumazine Synthase. It was imaged via CryoEM by David Bhella and his group at the University of Glasgow with the JEOL CryoARM300 and the DE-64 direct detection camera. The Bhella group reported a 2 Angstrom resolution for this reconstruction, and this has been released on EMDB. Images were acquired at 141 FPS with 2 x binning and electron counting. The reconstruction was performed with 16,258 particles.

What’s New

Explore Electron Microscopy Data Analysis with Carter Francis and the GLMS Webinar Series

From HyperSpy fundamentals to advanced 4D-STEM analysis, explore a five-part educational webinar series featuring Direct Electron’s Dr. Carter Francis.

UPCOMING WEBINAR: Autonomous MicroED with REyes

REyes (Reciprocal Eyes), a fully autonomous MicroED platform that streamlines crystal selection, diffraction data collection, and structure determination. Discover how automation is making high-quality MicroED faster, more efficient, and more accessible.

WHAT IS THE BEST DOSE RATE FOR SINGLE PARTICLE CRYO-EM?

Research paper from Florida State University finds large differences in resolution for different dose rates.

TRIPLE YOUR THROUGHPUT IN SINGLE-PARTICLE CRYOEM —WITHOUT BUYING A NEW MICROSCOPE

Single-particle cryo-EM plays a vital role in understanding biological structures and advancing drug discovery, vaccines, and therapeutics.

Direct Electron Heads to Tokyo for LEEM/PEEM-14

Direct Electron is heading to Tokyo for the 14th International Conference on LEEM/PEEM (LEEM/PEEM-14), taking place October 5–9, 2026, at the University of Tokyo’s Hongo Campus.
Bob Monteverde, Director of Sales at Direct Electron, will be attending alongside Shinya Kondo of our Japanese partner, TEGA Science.