The DE-64 is the world’s first and only true 8k × 8k direct detector with the widest field of view of any direct detector. Ideal for cryo-EM of very large viruses or cellular tomography, the DE-64 delivers user-adjustable full-frame streaming at up to 46 frames per second, and offers unparalleled performance for electron counting. With nearly 4x more particles in a single image, the expansive 67.1 megapixel field-of-view dramatically decreases the number of images needed for each single particle experiment and improves 3D reconstructions by significantly improving CTF fitting. The DE-64 has 6.5 μm pixels optimized for superior resolution (MTF) over a broad range of magnifications and exposure rates, and it includes an integrated Faraday plate.
The innovative movie-mode processing software enhances data quality through drift correction, per-particle motion correction, radiation damage compensation, and post-acquisition exposure setting. It allows for direct detection of primary electrons, a truly revolutionary advancement in TEM data quality. If needed, enable the optional module for single electron counting, which has a ~50:1 (300 kV) signal-to-noise ratio. The clarity and speed of the DE-64 offers the ultimate in high-performance imaging for the most demanding projects and highest-level research.
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